ADAR and colorectal cancer: To address this, we selected five validated ARcircs and detected their expression changes upon overexpression of the wildtype or mutant form of ADAR1/2 in MB231 (breast cancer cell line), MKN28 (gastric tubular adenocarcinoma cell line), SNU398 (hepatocellular carcinoma cell line), and HCT15 (colorectal cancer cell line).