THRB and Leber congenital amaurosis: Because THRB2 is expressed only in the cones in the retina [29, 32, 33], and Thrb2 deletion has been documented in cone protection against T3-induced cell death [10] and in mouse models of LCA and achromatopsia [16], we also included Thrb2−/− mice in this study to learn more about Thrb2 deletion-associated protection in an NaIO3-induced mouse model of AMD.