NLRP12 and uveitis: Histopathological scoring of eyes from immunized mice corroborated the increased severity of uveitis in Nlrp12−/− mice (Fig. 1C), which had more subretinal hemorrhages, perivascular and chorioretinal infiltrates (with granulomatous features), and extensive retinal damage (e.g. photoreceptor ablation and diffuse atrophy) (Fig. 1D).