AFP and neoplasm: Multivariate analysis demonstrated that tumour location (hazard ratio, 1.263; 95% CI, 1.005–1.587), lymphatic metastasis (hazard ratio, 6.229; 95% CI, 2.228–17.412), MVI (hazard ratio, 1.711; 95% CI, 1.330–2.202), satellite nodules (hazard ratio, 1.449; 95% CI, 1.018–2.063), HBeAg (hazard ratio, 1.639; 95% CI, 1.255–2.139), and AFP levels (hazard ratio, 1.421; 95% CI, 1.131–1.786) were independent risk factors for DFS (Table 3).