Besides, DRD4, ZNF132 and ZNF43 have been linked with other non-lung cancer types: DRD4, encoding dopamine receptor, is involved in early brain development and epigenetically repressed in pediatric CNS tumors [30]; it also has be identified as a potential epidriver in hepatocellular carcinoma [29]. This evidence concerns the gene ZNF43 and central nervous system neoplasm.