As shown in the figure, breast cancer patients with high levels of ITPR1 mRNA have high OS (HR = 0.65, 95% CI: 0.53–0.81, P = 9e-05), RFS (HR = 0.68, 95% CI: 0.61- 0.76, P = 5.4e-12) and DMFS (HR = 0.7, 95% CI: 0.58–0.85, P = 0.00032) (Fig. 4J-L, Supplementary Table 3). This evidence concerns the gene ITPR1 and breast carcinoma.