Although SIAH2 protein expression did not show a consistent pattern between WDLPS and DDLPS in the tissues and cell lines, SIAH2 mRNA is highly expressed in paraffin-embedded DDLPS tissue stromal cells, colocalizes with DDLPS tumor-associated macrophages and is expressed at higher levels in DDLPS compared to WDLPS tissues. Here, SIAH2 is linked to neoplasm.