Indirect coculture with MSCs was able to reverse the increase of CD4+ T cell-expressed miR-155 and miR-146a induced by in vitro ARDS stimulation of LPS and hypoxia, while the effect of MSCs on miR-155 suppression was attenuated by cotreatment with TGF-β1 neutralization (P < 0.05, Figure 5). The gene discussed is CD4; the disease is acute respiratory distress syndrome.