STING1 and influenza: Although the impact of aging on mitochondrial biology is multifaceted, our data reveal that the leaked mtDNA and the resultant aberrant STING activation play a central role in telomere‐related immunopathology, as blockade of mtDNA leakage or depletion of cytosolic mtDNA lessened the inflammatory response in Terc−/− macrophages following influenza infection.