AIRE and Autoimmunity: Knowing that both augmented mouse Aire expression from authentic Aire‐expressing cells (3xAire‐KI) and additive expression of human AIRE in MHC‐II+ APCs (i.e. mTECs and bone marrow‐derived APCs such as dendritic cells; huAIRE‐Tg) paradoxically showed a propensity to the development of organ‐specific autoimmunity, we searched for augmented and/or ectopic AIRE expression in human patients with autoimmune disease.