CD8A and cancer: For LGG patients, the infiltration level of B cells, plasma cells, CD8+ T cells, macrophages, endothelial cells, cancer-associated fibroblasts (CAFs) and dendritic cells was higher in high-risk group (Fig. 9a–d), while the situation of NK cells (Fig. 9a–d) and regulatory T (Treg) cells (Fig. 9a, d) was different between the various algorithms.