Day of euthanasia also significantly influenced all targets except Cox1; relative to placentae from mice infected at E6.5 (i.e., E15.5), transcripts for Ifnγ, Tnf, Il1β, Il10, and Cox2 in placentae from E8.5 infections (i.e., E16.5) were all elevated. The gene discussed is TNF; the disease is infection.