Here, we reported that all tau biomarkers were significantly higher in Alzheimer’s disease in comparison to other dementias and some differences were also observed within the non-Alzheimer’s disease dementia group; NTB t-tau was significantly lower in vascular dementia, and all mid-region fragments (MR t-tau, Innotest t-tau and Innotest p-tau181) in mixed dementia in comparison to unspecified dementia. This evidence concerns the gene MAPT and Alzheimer disease.