HSP90B2P and open-angle glaucoma: Specifically, various anti-HSP antibodies expressed in patients with RA are associated with the progressive degeneration of RGC, a characteristic of POAG,59 and T cell–mediated responses involved in the initiation of RA may be simultaneously involved in the onset of POAG.50 This is an important hypothesis to be confirmed in future studies with animal experiments or pathophysiological research.