To test if P2ry14+ SCP-like cells derived from human neurofibromas have altered ability to self-renew, we performed fluorescence-activated cells sorting (FACS) and sorted SCP-like cells into p75+/EGFR+/P2ry14- and p75+/EGFR+/P2ry14+ cells and plated them at low density to generate unattached spheres in vitro (Figure 1D–F). This evidence concerns the gene EGFR and plexiform neurofibroma.