Differential expression analysis in GSE14520 indicated that expression of MAP3K1, MAPK3K3, MAP3K5, MAP3K7, MAP3K8, MAP3K9, MAP3K10, MAP3P11, MAP3K14, and MAP3K15 was significantly different between HCC and normal liver tissues (Figure 2(a)). The gene discussed is MAP3K5; the disease is hepatocellular carcinoma.