In multivariable analysis, AAC score was independently associated with KCNJ5 mutations (β=-0.168, P=0.014), age (β=0.387, P<0.001), systolic blood pressure (β=0.171, P=0.010), and number of hypertension drugs (β=0.153, P=0.024). Here, KCNJ5 is linked to Hypertension.