As shown in Table 4, AAC score was related to several factors including KCNJ5 mutations (P<0.001), age (P<0.001), systolic blood pressure (P=0.020), duration of hypertension (P=0.001) and number of hypertension drugs (P=0.003) in univariate analysis. Here, KCNJ5 is linked to Hypertension.