The expression of PRMT1, CARM1, PRMT5, PRMT7, PRMT8 and PRMT9 were all elevated in rhabdomyosarcoma (96), CARM1 and its direct interaction with histone acetyltransferase PCAF jointly were also detected to exert an increased expression of myogenin gene and lead to rhabdomyosarcoma cell differentiation (9). This evidence concerns the gene PRMT5 and rhabdomyosarcoma.