Also, KEGG pathway analysis indicated that cell cycle pathways, immune-related pathways (B-cell receptor and T-cell receptor signaling pathway), and tumor-related pathways (pathway in cancer and VEGF, JAK-STAT, mTOR, MAPK, WNT, and NOTCH signaling pathways) were significantly enriched in the high-risk group (Figure 7B; Supplementary Figure 8). Here, PPIB is linked to neoplasm.