The slight disagreement in distributions of POU2F3 and YAP1 subtypes might originated from a possibilities of a clonal selection for a dominant transcription factor during tumor expression (17), as well as the inclusion of more combined SCLC histology samples in FFPE cohort, which was reported containing more POU2F3 and YAP1 expression specimens (12). Here, POU2F3 is linked to small cell lung carcinoma.