In NPC, TECs demonstrated enhanced capacity to recruit CTLs and Tregs via CXCL9–CXCR3 and CXCL10–CXCR3 while simultaneously inhibiting CTLs through PDL2–PD1 interaction, suggesting their role in the mediation of an immunosuppressive niche in the NPC microenvironment (18). The gene discussed is PDCD1; the disease is nasopharyngeal carcinoma.