In NPC, TECs demonstrated enhanced capacity to recruit CTLs and Tregs via CXCL9–CXCR3 and CXCL10–CXCR3 while simultaneously inhibiting CTLs through PDL2–PD1 interaction, suggesting their role in the mediation of an immunosuppressive niche in the NPC microenvironment (18). This evidence concerns the gene CXCL9 and nasopharyngeal carcinoma.