Among those complications, macular edema [OR = 11.25 (2.85–43.81), p = 0.0005], cataract [OR = 11.87 (2.37–59.49), p = 0.0026], and band keratopathy [OR = 12.89 (2.05–80.90), p = 0.0064] are the most significant being associated with anti-TNFα therapy; those occur in severest uveitis with chronic inflammation. The gene discussed is TNF; the disease is uveitis.