MYBPC3 and familial dilated cardiomyopathy: We performed a whole-exome sequencing (WES) to detect her genetic etiology and used minigene modeling and immunohistochemistry staining to verify the pathogenicity.<h4>Results</h4>We determined that the woman died of SCD caused by DCM due to an identified novel synonymous variant of <i>MYBPC3</i> (NM_000256.3: c.24A>C, p.P8P) in the deceased.