The results showed that a similar percentage of CD4+IL-2+, CD4+IFN-γ+, and CD8+IL-2+ T cells was detected in SSc patients with and without anti-Scl-70 antibody following stimulation with peptides derived from Scl-70 protein (Figures 2(a)–2(c)). This evidence concerns the gene CD4 and systemic sclerosis.