AKT1 and Familial prostate cancer: LncRNA Small Nucleolar RNA Host Gene 1 (SNHG1) activates Wnt/β-catenin and PI3K/Akt/mTOR signaling pathways by targeting EZH2 (Enhancer of zeste homolog 2), and promoting proliferation, apoptosis and autophagy of prostate cancer (PCa) cells (Chen et al., 2020a).