LncRNA Small Nucleolar RNA Host Gene 1 (SNHG1) activates Wnt/β-catenin and PI3K/Akt/mTOR signaling pathways by targeting EZH2 (Enhancer of zeste homolog 2), and promoting proliferation, apoptosis and autophagy of prostate cancer (PCa) cells (Chen et al., 2020a). The gene discussed is EZH2; the disease is Familial prostate cancer.