IL17A and atrial fibrillation: Furthermore, in LDH, which NP herniated with AF rupture, compared with the healthy controls, the elevated levels of Th17 lymphocytes and IL-17A correlated with the patients’ pain intensity of sciatica, suggesting that the rupture of the AF and herniation of the NP are initiators of an autoimmune response to a ruptured lumbar disc (Cheng et al., 2013).