Recently, it has been reported that anti-PD-L1 (programmed cell death-Ligand 1) immune checkpoint blockade can induce cancer cell ferroptosis responses by down-regulating SLC7A11 expression in cancer cells as a result of IFN-γ (Interferon γ) secreted by CD8+ T cells (Wang et al., 2019c). Here, IFNG is linked to cancer.