PAFAH1B1 and lissencephaly spectrum disorders: Although a certain degree of lissencephaly is presented in the human case described above, the GABAergic interneurons disruption pattern appears to be clearly altered and is similar to the one described in the Lis1/sLis1 mutant phenotype, showing that some mutations associated to the PAFAH1B1 gene can affect specially the cortical inhibitory component.