In almost all different types of lymphoma, MALT1 is required to cleave NF-κB negative regulators A20 and RelB (Coornaert et al., 2008), while it is less studied in solid tumors (Fontan et al., 2012; Di Pilato et al., 2019; Liu et al., 2020). The gene discussed is MALT1; the disease is lymphoma.