Currently, three mouse models mimic the histopathological features of PFBC: Slc20a2 (Jensen et al., 2013) and Myorg (Yao et al., 2018) knockouts, and PDGFB hypomorph (Pdgfbret/ret, retention motif knockout) (Keller et al., 2013). The gene discussed is PDGFB; the disease is bilateral striopallidodentate calcinosis.