Another recent study of 25 patients with autoimmune encephalitis (NMDAR, n = 10; LGI-1, n = 9; Caspr2, n = 3; both LGI1 and Caspr2, n = 1, GABA-bR, n = 1; AMPAR, n = 1), demonstrated elevated serum levels of NfL that correlated with elevated levels of CSF NfL (20). The gene discussed is CNTNAP2; the disease is autoimmune encephalitis.