Based upon data showing a retraction of the Tn repertoire following infection by Townsend et al, and Phetsouphanh et al, we can speculate regarding a possible “T cell depletion dependent enhancement” as the stimulated repertoire (which includes the T cells specific to SARS-Cov-2 epitopes, those activated by a bystander effect, and those also stimulated superantigenically and by complement) has lost a proportion of its Tn and is thereby able to quickly differentiate into T cell Effectors since there is no CD95L sink that the CD95 expression on Tn and Tscm offer (30–32, 54). This evidence concerns the gene FASLG and infection.