LGI1 and Cognitive impairment: Neural autoantibodies against the cell surface such as N-methyl-d-aspartate receptor (NMDAR), gamma aminobutyric acid B receptor (GABABR), α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR), leucine-rich glioma inactivated protein 1 (LGI1), and dipeptidyl-peptidase-protein-like 6 (DPPX) are often detected in patients suffering from worsening cognitive impairment (2, 3).