In the Src-transformed immortalized breast epithelial cells, Src phosphorylates STAT3 and phosphorylated STAT3 binds to the promoter region of LINC00520, thereby further promoting the expression of LINC00520 in BC, while depletion of STAT3 eliminates the up-regulation of LINC00520 induced by Src (8). The gene discussed is SRC; the disease is breast cancer.