No differences were observed also considering the magnitude of the response in both HCWs and RA patients (median CD4+IFN-γ+ HCWs: 0.001%, IQR 0.00–0.05 vs. median CD4+IFN-γ+ RA: 0.00%, IQR: 0.00–0.43, p = 0.5). This evidence concerns the gene CD4 and rheumatoid arthritis.