Meanwhile PPARγ phosphorylation can up-regulate lipid uptake of CD36 and SR-A1 related proteins, inhibit cholesterol efflux ABCA1 and ABCG1 related proteins, induce the expression of TNF-α, IL-1β and other inflammatory factors, and promote the formation of foam cells to accelerate the process of atherosclerosis (Choi et al., 2010, 2011; Banks et al., 2015). The gene discussed is PPARG; the disease is atherosclerosis.