In addition, RBP4 has shown promising value for cardiovascular disease diagnosis and treatment, such as predicting the risk of hypertension and coronary heart disease in the general population, and assessing the prognosis of patients with coronary heart disease and heart failure, etc. RBP4 is expected to be a new biomarker for cardiovascular disease in the future. The gene discussed is RBP4; the disease is coronary artery disorder.