SLC5A2 and type 2 diabetes mellitus: In 2019, an Asian perspective and expert recommendation [6] was published, which reviewed and consolidated the evidence for SGLT-2 inhibitors from CVOTs, large-scale real-world evidence (RWE) studies, as well as clinical trials in Asian populations, and recommended that SGLT-2 inhibitors should be considered early in the treatment of T2DM patients with multiple risk factors, as the drugs have multifactorial effects on blood pressure, weight, insulin sensitivity, and albuminuria.