Increasing IL-6 (OR 1.02, 95% CI 1.00 to 1.03, P = 0.047) and D-dimer (OR 7.26, 95% CI 1.11 to 47.30, P = 0.04) also independently predicted mortality in models which included respiratory parameters and ARDS etiology (Model 2 and 3, Supplementary Table 2). Here, IL6 is linked to acute respiratory distress syndrome.