The top keywords with the highest frequency were as follows: prevalence, conjunctivitis, 2-phase 3 trials, persistent asthma, safety, efficacy, quality of life, care, severity, daily practice, eczema herpeticum, epidemiology, IL-13, risk, allergic conjunctivitis, asthma, azathioprine, biomarkers, IL-4, long-term, monoclonal antibody, and reliability. The gene discussed is IL4; the disease is asthma.