Compared with survivors, non-survivors were significantly older with higher rates of female sex, obesity, smoking history, malignancies, CKD, DM, chronic viral hepatitis, liver cirrhosis and hepatic failure, COPD, ILD, HF, cIHD and sequalae of CVD (old cerebrovascular events), GC administration, and albumin preparation administration. This evidence concerns the gene ALB and obesity due to melanocortin 4 receptor deficiency.