HSPA6 and hand, foot and mouth disease: To investigate the inducible effect of other HFMD-associated viruses on HSPA6 expression, RD or Vero cells were infected with different HFMD-associated viruses including EV71 C4 strain, EV71 BrCr strain, CVA6, CVA10, CVA16, and CVB1-3 at MOI of 0.2 for 8 h, and then subjected to RT-PCR analysis for HSPA6 mRNA level.