1. Reduced LDL, triglycerides, cholesterol, glucose, insulin and insulin resistance levels as well as increased HDL and SHBG 2. “BBR combined with Chinese prescription Cang Fu Dao Tan Tang reduced BMI, HOMA-IR, FIN-D2D, T, LH, and LH: FSH, LDL-C, and the effect on TG, LDL-C, and HDL-C” 3. “Mechanisms are still unclear”. The gene discussed is PLOD1; the disease is Insulin resistance.