1. Ameliorated the essential hormones in the menstrual cycle: FSH, LH, E2, P4 and T, and thus their effect in infertility treatment 2. Reduced LDL, triglycerides, cholesterol and glucose levels in the serum, and helped manage obesity pattern in PCOS rats. Here, PLOD1 is linked to obesity due to melanocortin 4 receptor deficiency.