Quercetin, tryptophan, and resveratrol are the prototypical AhR ligands that can modulate and promote their nuclear translocation (28, 37, 103), and flavipin has recently been shown to ameliorate autoimmunity in vivo via aryl receptor gene activation (80); hence, their calculated binding energies of −6.89, −5.62, −6.64, and −4.56 kcal/mol were considered as positive controls in our in silico screening. This evidence concerns the gene AHR and Autoimmunity.