PPARA and Disorder of lipid metabolism: By stimulating the sirtuin 1 (SIRT1)/peroxisome proliferator-activated receptor alpha (PPARα)/Fibroblast growth factor 21 (FGF21) pathway, APS could alleviate lipid metabolism disorder, notably, by increasing hepatic glycolipid metabolism, reducing inflammation, and lipid droplet deposition (Gu et al., 2015).