Interestingly, there is another study also demonstrated that resveratrol is obviously competent at suppressing TNF-β-induced activation of tumor-promoting transcription factor NF-κB, and thus mediating EMT signatures containing Slug, E-cadherin, and vimentin, resulting in exerting inhibitory effects of EMT program in CRC HCT116 and HCT116R cell lines (Buhrmann et al., 2018). This evidence concerns the gene NFKB1 and colorectal carcinoma.