Similarly, It was also found that oxymatrine in combination with 5-Fu treatment efficiently regulated tumor cells EMT through effective modulation of the expressions of Snai2, vimentin, E-cadherin, and p-NF-κB p65 in HCT-8/5-Fu cells (Liang et al., 2020). The gene discussed is NFKB1; the disease is neoplasm.