TWIST1 and colorectal carcinoma: In an additional study (Chen T. et al., 2020), curcumin significantly reduced the expression of EMT-related genes containing Wnt3a, Snail1, and Twist, N-cadherin, and vimentin, as well as nuclear translocation levels of ß-catenin, while remarkably increasing E-cadherin expression, consequently suppressing EMT progression in SW480 CRC cells.