[Anacardiaceae] water extract (RCWE) was strongly effective in restraining metastatic and invasive characteristics of CRC cells by modulating EMT-related phenotypes, and suppressed MMP-2 and MMP-9 activities, as well as it also reduced the metastatic tumor nodules in the lungs of CRC lung metastatic model mice (Mun et al., 2019). This evidence concerns the gene MMP9 and neoplasm.