CDH2 and neoplasm: The previous report confirmed that triptolide treatment exerted inhibitory effects on tumor metastasis via blocking the activation of Wnt/β-catenin and NF-κB signalings, subsequently mediating EMT-related indicators expressions containing E-cadherin, vimentin, and N-cadherin in HT-29 and SW480 cells (Qi and Li, 2019).