CDH2 and neoplasm: There is another study confirmed that JSD notably repressed the migration and invasion of SW480 cells and reversed the EMT status through mediating the EMT-associated genes containing the E-Cadherin, N-Cadherin, and transcriptional coactivator with the PDZ-binding motif expressions in both the SW480 cells and tumor tissues of liver metastasis colon cancer model mice (Yuan et al., 2019c).