All this is extremely important because MBD2 was found to be highly expressed in pulmonary macrophages of patients with COVID19 and that the loss of MBD2 leads to a marked reduction in the accumulation of M2 macrophages in the lung, with a reduction in fibrotic commitment (Wang et al., 2021b; McErlean et al., 2021). This evidence concerns the gene MBD2 and COVID-19.