GJA1 and myocardial ischemia: Cx43 is the most predominant gap junction protein among various types of connexins, and has been shown to play essential roles in coordinating activities of cardiovascular tissues, key among them being selective inhibition of Cx43 hemichannels by Gap19 and its impact on myocardial ischemia/reperfusion injury %J Basic Research in Cardiology (Wang et al. 2013).