The absence of coexpression of TUBD1 a and b (Vab) isoforms is significantly associated with the risk of developing DR, specifically proliferative retinopathy, whereas the coexpression of TUBD1 isoforms a, b, and d (Vabd) has been associated with risk for developing nonproliferative retinopathy [16]. The gene discussed is TUBD1; the disease is retinal disorder.