Yta7 has a human homologue ATAD2 (ATPase family AAA+ domain-containing protein 2), which is an emerging oncogene and has been associated with many cancers of different origins.8,9 ATAD2 levels in normal proliferating cells are tightly controlled by mitogenic factors via the retinoblastoma (RB) - E2 transcription factor (E2F) pathway. Here, ATAD2 is linked to cancer.